1236147-01-5Relevant academic research and scientific papers
Total synthesis of enigmazole a from cinachyrella enigmatica. Bidirectional bond constructions with an ambident 2,4-disubstituted oxazole synthon
Skepper, Colin K.,Quach, Tim,Molinski, Tadeusz F.
supporting information; experimental part, p. 10286 - 10292 (2010/09/06)
The first total synthesis of the cytotoxic marine macrolide enigmazole A has been completed in 22 steps (longest linear sequence). The sensitive, densely functionalized 2,4-disubstituted oxazole fragment was constructed using an efficient Negishi-type cou
