1236149-07-7Relevant academic research and scientific papers
Efficient synthesis of 9-aryl-6-(2-fluorophenyl)-1,2,4-triazolo[4,3-a] [1,8]naphthyridines using chloramine-T under microwave irradiation
Mogilaiah,Dhanaja,Srivani,Chandra, A. Vinay
experimental part, p. 500 - 504 (2010/11/04)
A simple and highly efficient procedure has been described for the synthesis of 9-aryl-6-(2-fliuorophenyl)-1,2,4-triazolo[4,3-a][1,8]naphthyridines 8 by oxidation of the corresponding aryl aldehyde 3-(2-fluorophenyl)-1,8- naphthyridin-2-ylhydrazones 7 with chloramines-T in ethanol under microwave irradiation. The products are obtained in good yields and in state of high purity. The structures of the compounds 3-8 have been established on the basis of spectral (IR, 1H NMR and MS) and analytical data.
