1236206-95-3Relevant academic research and scientific papers
Efficient formal synthesis of (±)-axamide-1 and (±)- axisonitrile-1 via an intramolecular Hosomi-Sakurai reaction
Takahashi, Kazunori,Takeda, Kentaro,Honda, Toshio
scheme or table, p. 3542 - 3544 (2010/08/07)
A formal synthesis of (±)-axamide-1 and (±)-axisonitrile-1 was achieved by using an intramolecular Hosomi-Sakurai reaction of the allylsilane derivative, as a key step, in which [(3-but-3-en-1-yl-3- methylcyclohex-1-en-1-yl)methyl](trimethyl)silane was transformed to a bicyclic compound possessing a core carbon framework under the oxidative dihydroxylation reaction conditions, in one step.
