1236217-56-3Relevant articles and documents
Repairing faulty genes by aminoglycosides: Development of new derivatives of geneticin (G418) with enhanced suppression of diseases-causing nonsense mutations
Nudelman, Igor,Glikin, Dana,Smolkin, Boris,Hainrichson, Mariana,Belakhov, Valery,Baasov, Timor
experimental part, p. 3735 - 3746 (2010/08/03)
New pseudo-di- and pseudo-trisaccharide derivatives of the aminoglycoside drug G418 were designed, synthesized and their ability to readthrough nonsense mutations was examined in both in vitro and ex vivo systems, along with the toxicity tests. Two novel