1236223-53-2Relevant academic research and scientific papers
An alkynyliodide cycloaddition strategy for the construction of iodoisoxazoles
Crossley, James A.,Browne, Duncan L.
supporting information; experimental part, p. 5414 - 5416 (2010/10/04)
(Figure presented) The thermally promoted cycloaddition between alkynyliodides and nitrile oxides is reported. The process offers excellent regioselectivity and a broad scope with respect to both the iodoalkynes and chloro-oximes. Further functionalization of the highly decorated iodoisoxazole motifs can be achieved via Suzuki cross-coupling.
