1236262-83-1 Usage
Physical properties
white to off-white crystalline powder
Use
local anesthetic and analgesic agent
Mechanism of action
inhibits nerve conduction by blocking sodium channels in neuron membranes
Effects
reversible loss of sensation in the area where it is applied
Common applications
topical creams and ointments for relief of pain and discomfort associated with minor skin irritations, burns, and insect bites
Investigated use
reducing pain associated with medical procedures and surgeries
Check Digit Verification of cas no
The CAS Registry Mumber 1236262-83-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,6,2,6 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1236262-83:
(9*1)+(8*2)+(7*3)+(6*6)+(5*2)+(4*6)+(3*2)+(2*8)+(1*3)=141
141 % 10 = 1
So 1236262-83-1 is a valid CAS Registry Number.
1236262-83-1Relevant articles and documents
Chiral Thioureas Promote Enantioselective Pictet-Spengler Cyclization by Stabilizing Every Intermediate and Transition State in the Carboxylic Acid-Catalyzed Reaction
Klausen, Rebekka S.,Kennedy, C. Rose,Hyde, Alan M.,Jacobsen, Eric N.
, p. 12299 - 12309 (2017/09/12)
An investigation of the mechanism of benzoic acid/thiourea co-catalysis in the asymmetric Pictet-Spengler reaction is reported. Kinetic, computational, and structure-activity relationship studies provide evidence that rearomatization via deprotonation of