Cas 1236264-75-7,4-((4-(3,4-dihydroquinolin-1(2H)-yl)-6-(2-(4-methylpiperazin-1-yl)ethylamino)-1,3,5-triazin-2-ylamino)methyl)-N-ethyl-N-m-tolylbenzamide

1236264-75-7

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Basic information

Product Name: 4-((4-(3,4-dihydroquinolin-1(2H)-yl)-6-(2-(4-methylpiperazin-1-yl)ethylamino)-1,3,5-triazin-2-ylamino)methyl)-N-ethyl-N-m-tolylbenzamide
Synonyms: 4-((4-(3,4-dihydroquinolin-1(2H)-yl)-6-(2-(4-methylpiperazin-1-yl)ethylamino)-1,3,5-triazin-2-ylamino)methyl)-N-ethyl-N-m-tolylbenzamide
CAS NO:1236264-75-7
Molecular Formula:
Molecular Weight: 619.813
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 4-((4-(3,4-dihydroquinolin-1(2H)-yl)-6-(2-(4-methylpiperazin-1-yl)ethylamino)-1,3,5-triazin-2-ylamino)methyl)-N-ethyl-N-m-tolylbenzamide(CAS DataBase Reference)
NIST Chemistry Reference: 4-((4-(3,4-dihydroquinolin-1(2H)-yl)-6-(2-(4-methylpiperazin-1-yl)ethylamino)-1,3,5-triazin-2-ylamino)methyl)-N-ethyl-N-m-tolylbenzamide(1236264-75-7)
EPA Substance Registry System: 4-((4-(3,4-dihydroquinolin-1(2H)-yl)-6-(2-(4-methylpiperazin-1-yl)ethylamino)-1,3,5-triazin-2-ylamino)methyl)-N-ethyl-N-m-tolylbenzamide(1236264-75-7)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1236264-75-7(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1236264-75-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,6,2,6 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1236264-75:
(9*1)+(8*2)+(7*3)+(6*6)+(5*2)+(4*6)+(3*4)+(2*7)+(1*5)=147
147 % 10 = 7
So 1236264-75-7 is a valid CAS Registry Number.

1236264-75-7Upstream product

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1236264-75-7Relevant academic research and scientific papers

2,4-DIAMINO-1,3,5-TRIAZINE AND 4, 6-DIAMINO-PYRIMIDINE DERIVATIVES AND THEIR USE AS AGGRECANASE INHIBITORS

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Page/Page column 132-133, (2010/08/08)

The invention is directed to compounds of formula (I): that modulate, e.g., inhibit, aggrecanase proteolytic activity, which is implicated in joint diseases including osteoarthritis, joint injury, reactive arthritis, acute pyrophosphate arthritis, psoriatic arthritis, and rheumatoid arthritis. The current invention also relates to processes for making the compounds of the invention and to pharmaceutical compositions containing these compounds. The present invention further provides methods of treating diseases associated with aggrecanase activity, e.g., osteoarthritis and other joint diseases, using the compounds of the invention.

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