1236267-13-2Relevant academic research and scientific papers
Reactions of N-arylmaleimides with 3-amino-1,2,4-triazole and 2-aminobenzimidazole
Rudenko, Roman V.,Komykhov, Sergey A.,Musatov, Vladimir I.,Konovalova, Irina S.,Shishkin, Oleg V.,Desenko, Sergey M.
experimental part, p. 888 - 895 (2011/10/02)
Figure represented. The reaction of 3-amino-1,2,4-triazole (1) with N-arylmaleimides leads to azolopyrimidines 4 and 5. The 2-aminobenzimidazole (2) in the reaction with 3 gives the pyrimidobenzimidazoles 6. In similar conditions, the reaction of amine 2 with maleic anhydride (7) leads to formation of 2-oxo-1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole-4-carboxylic acid (8). The structures of 4, 5, 6, and 8 were proved by X-Ray and NOE NMR measurements. J. Heterocyclic Chem., (2011)
