1236274-18-2Relevant academic research and scientific papers
1,3-Dipolar cycloadditions of 2-thio-3-chloroacrylamides with diazoalkanes
Kissane, Marie,Lawrence, Simon E.,Maguire, Anita R.
supporting information; experimental part, p. 2735 - 2748 (2010/08/21)
2-Thio-3-chloroacrylamides undergo 1,3-dipolar cycloadditions with diazoalkanes leading to a series of novel pyrazolines and pyrazoles. The mechanistic and synthetic features of the cycloadditions to the 2-thio-3-chloroacrylamides at both the sulfide and sulfoxide levels of oxidation are rationalised on the basis of the nature of the substituents.
