123629-42-5

Basic information

• Product Name: ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
• Synonyms: ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate;ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
• CAS NO: 123629-42-5
• Molecular Formula: C₁₅H₁₈N₂O₅
• Molecular Weight: 306.31382
• Mol File: 123629-42-5.mol
• Article Data: 91

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate(123629-42-5)
• EPA Substance Registry System: ethyl 4-(4-hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate(123629-42-5)

Safety Data

• Hazardous Substances Data: 123629-42-5(Hazardous Substances Data)

Usage

Uses

Ethyl 4-(4-Hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate is an inhibitor of in-vitro thymidine phosphorylase, kinesin Eg5 and urease.

Upstream product

• 141-97-9 ethyl acetoacetate 
• 121-33-5 vanillin 
• 57-13-6 urea 

Downstream Products

• 1190370-90-1 C₃₃H₂₈N₄O₉ 
• 1190370-87-6 C₃₃H₃₄N₆O₅ 
• 1190370-89-8 C₂₉H₂₈N₈O₅ 
• 1190370-86-5 C₃₁H₃₀N₆O₅ 

Relevant articles and documents

Silica-supported ionic liquid Si-[SbSipim][PF6]: An efficient catalyst for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones

Silica-supported sulfonic acid-functional ionic liquid (Si-[SbSipim] [PF6]) was found to be an effective catalyst for the synthesis of 3,4-dihydropyrimidine-2-(1H)-ones via a one-pot, three-component Biginelli reaction. The catalyst could be ea

New procedure for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones by Biginelli reaction

A practical green chemistry procedure for synthesis of 3,4- dihydropyrimidin-2(1H);-ones in good yields was successfully carried out in micellar systems according to the Biginelli reaction using β-ketoester, urea and appropriate aromatic aldehyde in the p

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We report here Dowex 50W-mediated efficient synthesis of 4-aryl 3,4-dihydropyrimidones in water for the first time in a one-pot operation.

Copper (II) sulfamate: An efficient catalyst for the one-pot synthesis of 3,4-dihydropyrimidine-2(1H)-ones and thiones

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The present study focuses on the synthesis, characterization and biological evaluation of dihydropyrimidinone derivative ethyl-4-(4- hydroxy-3-methoxyphenyl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate from vanillin, ethylacetoacetate and ur

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An efficient protocol for the synthesis, biological screening and molecular docking studies of 3,4-dihydropyrimidine-2-one/thione derivatives

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