1236348-75-6

Basic information

• Product Name: 3-(diphenylphosphoryl)-1-phenylhex-1-yn-3-ol
• CAS NO: 1236348-75-6
• Molecular Weight: 374.419
• Mol File: 1236348-75-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(diphenylphosphoryl)-1-phenylhex-1-yn-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(diphenylphosphoryl)-1-phenylhex-1-yn-3-ol(1236348-75-6)
• EPA Substance Registry System: 3-(diphenylphosphoryl)-1-phenylhex-1-yn-3-ol(1236348-75-6)

Safety Data

• Hazardous Substances Data: 1236348-75-6(Hazardous Substances Data)

Upstream product

• 14252-32-5 1-phenyl-hex-1-yn-3-one 
• 4559-70-0 Diphenylphosphine oxide 

Relevant articles and documents

Reaction of secondary phosphine oxides with acylacetylenes

Secondary phosphine oxides reacted with 1-alkanoyl-2-phenylacetylenes in chemoselective fashion under mild conditions (20°C, THF) in the absence of a catalyst (diphenylphosphine oxide) or in the presence of potassium hydroxide [bis(2-phenylethyl)phosphine oxide] to give 1-alkyl-1-diphenyl(or 2-phenylethyl)-phosphoryl-3-phenylprop-2-yn-1-ols in up to 96% yield. The reaction of diphenylphosphine oxide with 1-alkanoyl-2-phenylacetylenes in the system KOH-THF (20°C) afforded not only adducts at the carbonyl group but also products of double α,β-addition at the triple bond, 2,3-bis(diphenylphosphoryl)-3-phenylpropan-1-ones.