1236349-63-5

Basic information

• Product Name: 4-(2-(2-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)ethoxy)ethoxy)benzonitrile
• Synonyms: 4-(2-(2-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)ethoxy)ethoxy)benzonitrile
• CAS NO: 1236349-63-5
• Molecular Weight: 380.4
• Mol File: 1236349-63-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2-(2-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)ethoxy)ethoxy)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-(2-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)ethoxy)ethoxy)benzonitrile(1236349-63-5)
• EPA Substance Registry System: 4-(2-(2-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)ethoxy)ethoxy)benzonitrile(1236349-63-5)

Safety Data

• Hazardous Substances Data: 1236349-63-5(Hazardous Substances Data)

Upstream product

• 767-00-0 4-cyanophenol 
• 86927-04-0 2-(2-(2-(2-bromoethoxy)ethoxy)ethyl)-isoindole-1,3(2H)-dione 

Downstream Products

• 1236349-64-6 C₂₃H₂₆N₂O₆*ClH 

Relevant articles and documents

Hoechst-IR: An imaging agent that detects necrotic tissue in vivo by binding extracellular DNA

(Equation Presented). Cell necrosis is central to the progression of numerous diseases, and imaging agents that can detect necrotic tissue have great clinical potential. We demonstrate here that a small molecule, termed Hoechst-IR, composed of the DNA binding dye Hoechst and the near-infrared dye IR-786, can image necrotic tissue in vivo via fluorescence imaging. Hoechst-IR detects necrosis by binding extracellular DNA released from necrotic cells and was able to image necrosis generated from a myocardial infarction and lipopolysaccharide/d-galactosamine (LPS-GalN) induced sepsis.