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1-(2-chloro-3-fluoro-4-pyridyl)ethanone, also known as CFE, is a synthetic intermediate with the molecular formula C7H6ClFNO. It is a pale yellow liquid characterized by a molecular weight of 169.58 g/mol and strong electrophilic properties. CFE is utilized in the pharmaceutical industry for the production of various active pharmaceutical ingredients and serves as a building block in the synthesis of pyridine-based compounds. Its structural features make it a valuable compound for the development of new pharmaceutical molecules and agrochemicals.

1236770-00-5

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1236770-00-5 Usage

Uses

Used in Pharmaceutical Industry:
1-(2-chloro-3-fluoro-4-pyridyl)ethanone is used as a synthetic intermediate for the manufacturing of various active pharmaceutical ingredients. Its strong electrophilic properties and structural features make it a key component in the development of new pharmaceutical molecules.
Used in Organic Chemistry Research:
1-(2-chloro-3-fluoro-4-pyridyl)ethanone is used as an important reagent in organic chemistry, contributing to various research and industrial applications. Its unique structural properties allow for the synthesis of complex organic compounds and the exploration of novel chemical reactions.
Used in Agrochemical Development:
1-(2-chloro-3-fluoro-4-pyridyl)ethanone is used as a building block in the development of new agrochemicals, thanks to its strong electrophilic properties and its role in the synthesis of pyridine-based compounds, which are often found in various agrochemical products.

Check Digit Verification of cas no

The CAS Registry Mumber 1236770-00-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,6,7,7 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1236770-00:
(9*1)+(8*2)+(7*3)+(6*6)+(5*7)+(4*7)+(3*0)+(2*0)+(1*0)=145
145 % 10 = 5
So 1236770-00-5 is a valid CAS Registry Number.

1236770-00-5Downstream Products

1236770-00-5Relevant academic research and scientific papers

Synthesis of 3-Chloro-4-fluoro-7,8-dihydro-6 H -isoquinolin-5-one and Its Derivatives

Velcicky, Juraj,Pflieger, Daniel

, p. 1397 - 1401 (2010)

Synthesis of novel 3-chloro-4-fluoro-7,8-dihydro-6H-isoquinolin-5-one and its derivatives using sequential ortho-formylation/ortho-allylation reactions of 2-chloro-3-fluoropyridine and ring-closing metathesis is described.

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