1236861-75-8 Usage
Uses
Used in Pharmaceutical Industry:
3-(3-Fluorophenoxy)-azetidine HCl is used as a reactant for the preparation of dihydropyrazolopyrimidinone derivatives, which are known for their potential as PDE9 inhibitors. PDE9 inhibitors have been studied for their therapeutic effects in various conditions, including cognitive disorders and diabetes-related complications. The use of 3-(3-Fluorophenoxy)-azetidine HCl in the synthesis of these derivatives highlights its importance in the development of novel pharmaceutical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1236861-75-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,6,8,6 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1236861-75:
(9*1)+(8*2)+(7*3)+(6*6)+(5*8)+(4*6)+(3*1)+(2*7)+(1*5)=168
168 % 10 = 8
So 1236861-75-8 is a valid CAS Registry Number.
1236861-75-8Relevant academic research and scientific papers
PDE9I WITH IMIDAZO PYRAZINONE BACKBONE
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Page/Page column 38; 39, (2013/04/25)
This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The pres
AMINO-HETEROCYCLIC COMPOUNDS
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Page/Page column 29-30, (2010/08/07)
The invention provides PDE9-inhibiting compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, A, and n are as defined herein. Pharmaceutical compositions containing the compounds of Formula I, and uses thereof in treating neurodegenerative and cognitive disorders, such as Alzheimer's disease and schizophrenia, are also provided.