1236874-93-3Relevant academic research and scientific papers
Switching reaction pathways of trifluoromethylated thiobenzanilides by choice of different oxidative systems
Zhu, Jiangtao,Xie, Haibo,Li, Shan,Chen, Zixian,Wu, Yongming
body text, p. 306 - 309 (2011/06/20)
Trifluoromethylated thiobenzanilides are efficiently converted to 2-trifluoromethylbenzothiazoles via intramolecular oxidative cyclization under CAN/NaHCO3 oxidation, while the dimerized products with "-S-S-" bond linkage are obtained when PIDA
A general and straightforward method for the synthesis of 2-trifluoromethylbenzothiazoles
Zhu, Jiangtao,Chen, Zixian,Xie, Haibo,Li, Shan,Wu, Yongming
supporting information; experimental part, p. 2434 - 2436 (2010/07/10)
An efficient one-pot method for the synthesis of 2- trifluoromethylbenzothiazoles by the treatment of trifluoromethylimidoyl chlorides with sodium hydrosulfide hydrate using PdCl2 as the sole catalyst in DMSO is described. The reaction proceeds via thiolation/C-H bond functionalization/C-S bond formation in moderate to high yields with good functional group tolerance.
