123718-19-4

Upstream product

• 141045-81-0 Dimethyl (2E,6E)-2-Methyl-2,6-octadienedioate 
• 113709-50-5 Lithium N-benzyl-N-(trimethylsilyl)amide 
• 26505-44-2 dimethyl (E,E)-octa-2,6-diendioate 
• 74-88-4 methyl iodide 
• 85757-66-0 Methyl 2-Methyl-6-oxo-2-hexenoate 

Downstream Products

• 490-09-5 (+/-)-dihydronepetalactone 
• 490-09-5 4,7-dimethylhexahydrocyclopenta[c]pyran-1(3H)-one 
• 123718-20-7 2-(Benzyl-methyl-amino)-5-(1-methoxycarbonyl-ethyl)-cyclopentanecarboxylic acid methyl ester 

Relevant academic research and scientific papers

New Type of Cyclization of α,β,χ,ψ-Unsaturated Dioic Acid Esters through Tandem Conjugate Additions by Using Lithium N-Benzyl-N-(trimethylsilyl)amide as a Nitrogen Nucleophile

Treatment of dimethyl (2E,6E)-2,6-octadienedioate with lithium N-benzyl-N-(trimethylsilyl)amide (LSA) gave 5-exo-trig ring closure products, methyl 3-(N-benzylamino)-2-(methoxycarbonyl)cyclopentane-1-acetates, through tandem conjugate additions.The relate

Cyclisation of α,β,χ,ψ-Unsaturated Dioic Acid Esters via Tandem Conjugate Additions by using Lithium N-Benzyltrimethylsilylamide (LSA) as a Nitrogen Nucleophile and its Application to a Total Synthesis of (+/-)-Dihydronepetalactone and (+/-)-Isodihydronep

A stereoselective total synthesis of (+/-)-dihydronepetalactone and (+/-)-isodihydronepetalactone has been accomplished by utilising a novel cyclisation procedure; a reaction of octadiene-2,6-dioic acid esters with lithium N-benzyltrimethylsilylamide (LSA