123772-37-2Relevant academic research and scientific papers
Human constitutive androstane receptor agonist DL5016: A novel sensitizer for cyclophosphamide-based chemotherapies
Liang, Dongdong,Li, Linhao,Lynch, Caitlin,Mackowiak, Bryan,Hedrich, William D.,Ai, Yong,Yin, Yue,Heyward, Scott,Xia, Menghang,Wang, Hongbing,Xue, Fengtian
, p. 84 - 99 (2019/06/27)
The DNA alkylating prodrug cyclophosphamide (CPA), alone or in combination with other agents, is one of the most commonly used anti-cancer agents. As a prodrug, CPA is activated by cytochrome P450 2B6 (CYP2B6), which is transcriptionally regulated by the
CAR ACTIVATOR AGENTS FOR CYCLOPHOSPHAMIDE-BASED TREATMENTS OF CANCER
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Page/Page column 84; 85; 125, (2019/01/10)
The invention relates to selective small molecule human constitutive androstane receptor (hCAR) activators of Formula (I) or (II), pharmaceutical compositions thereof, and use thereof for the treatment of hematologic malignancies and other cancers. The sm
Imidazothiazole Carbamates and Acylureas as Potential Insect Control Agents
Andreani, Aldo,Rambaldi, Mirella,Carloni, Patricia,Greci, Lucedio,Stipa, Pierluigi
, p. 525 - 529 (2007/10/02)
Imidazothiazole carbamates and acylureas were prepared by reaction of 5-hydroxymethylimidazothiazole and imidazothiazole-5-carboxyamide with arylisocyanates.The products formed depend from the substituent bonded at the 6 position of t
