1237740-96-3

Basic information

• Product Name: (R)-1-(2-hydroxyphenyl)-3,7-dimethyloctane-1,6-dione
• Synonyms: (R)-1-(2-hydroxyphenyl)-3,7-dimethyloctane-1,6-dione
• CAS NO: 1237740-96-3
• Molecular Weight: 262.349
• Mol File: 1237740-96-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-1-(2-hydroxyphenyl)-3,7-dimethyloctane-1,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(2-hydroxyphenyl)-3,7-dimethyloctane-1,6-dione(1237740-96-3)
• EPA Substance Registry System: (R)-1-(2-hydroxyphenyl)-3,7-dimethyloctane-1,6-dione(1237740-96-3)

Safety Data

• Hazardous Substances Data: 1237740-96-3(Hazardous Substances Data)

Upstream product

• 95-56-7 2-hydroxybromobenzene 
• 499-54-7 (4R)-7-isopropyl-4-methyloxepan-2-one 

Relevant articles and documents

Synthesis of substituted chromanones: An organocatalytic aldol/oxa-michael reaction

(Equation Presented). A diastereoselective organocatalytic aldol/oxa-Michael reaction has been developed to efficiently deliver medicinally relevant 2,3-ring-substituted chromanones. Development of this synthetic strategy revealed an unexpected kinetic anti-Saytzeff elimination; an origin for the observed selectivity is suggested on the basis of the results of quantum chemical calculations. This unusual kinetic selectivity necessitated an isomerization protocol that in turn led to the discovery of an intriguing Pd-mediated isomerization/intramolecular Friedel-Crafts-type alkylation.