1237816-26-0

Basic information

• Product Name: C₂₀H₂₁NO
• CAS NO: 1237816-26-0
• Molecular Weight: 291.393
• Mol File: 1237816-26-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₁NO(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₁NO(1237816-26-0)
• EPA Substance Registry System: C₂₀H₂₁NO(1237816-26-0)

Safety Data

• Hazardous Substances Data: 1237816-26-0(Hazardous Substances Data)

Upstream product

• 513-81-5 2,3-dimethyl-buta-1,3-diene 
• 15561-72-5 3-benzylbenzo[d][1,2,3]triazin-4(3H)-one 

Relevant articles and documents

Nickel-catalyzed denitrogenative annulation reactions of 1,2,3-Benzotriazin-4(3 H)-ones with 1,3-dienes and alkenes

(Figure presented) 1,2,3-Benzotriazin-4(3H)-ones react with 1,3-dienes in the presence of a nickel(0)/phosphine complex to give a variety of 3,4-dihydroisoquinolin-1(2H)-ones. Oxidative insertion of nickel(0) into the triazinone moiety prompts extrusion of dinitrogen to give a five-membered ring azanickelacyclic intermediate. Subsequent insertion of 1,3-dienes into the nickel-carbon bond followed by allylic amidation affords 3,4-dihydroisoquinolin- 1(2H)-ones. Alkenes also undergo insertion into the five-membered ring azanickelacyclic intermediate, and subsequent reductive elimination gives 3-substituted 3,4-dihydroisoquinolin-1(2H)-ones.