123796-61-2Relevant academic research and scientific papers
A self-immolative spacer that enables tunable controlled release of phenols under neutral conditions
Schmid, Kyle M.,Jensen, Lasse,Phillips, Scott T.
experimental part, p. 4363 - 4374 (2012/06/18)
A current challenge in the area of responsive materials is the design of reagents and polymers that provide controlled release of phenols in environments that are less polar than water. In these contexts, a molecular strategy that enables release of nearl
Inhibitors of α4 mediated cell adhesion
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, (2008/06/13)
The present invention relates to a pharmaceutical composition comprising as an active ingredient a compound of formula (I), wherein Ring A is an aromatic or a heterocyclic ring; Q is a bond, carbonyl, lower alkylene, lower alkenylene, —O-(lower alkylene)-, etc.; n is 0, 1 or 2; Z is oxygen or sulfur, W is oxygen, sulfur, —CH═CH—, —NH— or —N═CH—; R1, R2and R3are the same or different and are hydrogen, halogen, hydroxyl, a substituted or unsubstituted lower alkyl group, a substituted or unsubstituted lower alkoxy group, a substituted or unsubstituted amino group, etc.; R4is tetrazolyl, carboxyl group, amide or ester; R5is hydrogen, nitro, amino, hydroxyl, lower alkanoyl, lower alkyl etc.; R6is selected from (a) a substituted or unsubstituted phenyl group, (b) a substituted or unsubstituted pyridyl group, (c) a substituted or unsubstituted thienyl group, (d) a substituted or unsubstituted benzofuranyl group, etc.; or a pharmaceutically acceptable salt thereof.
Synthetic Approaches to the Naphthyl-isoquinoline Alkaloids. Part 1. Dehydroancistrocladisine
Rizzacasa, Mark A.,Sargent, Melvyn V.
, p. 841 - 844 (2007/10/02)
A synthesis of (+/-)-7-(4,5-dimethoxy-2-methyl-1-naphthyl)-6,8-dimethoxy-1,3-dimethylisoqinoline (dehydroancistrocladisine) 19, the racemic form of a degradation product of the unusual naphthylisoquinoline alkaloid ancistrocladisine 3, is recorded.The key
Synthetic Approaches to the Alkaloids of the Ancistrocladacea: Dehydroancistrocladisine
Rizzacasa, Mark,Sargent, Melvyn V.
, p. 301 - 302 (2007/10/02)
Dehydroancistrocladisine, a derivative of ancistrocladisine which is a member of the unusual naphthyl-isoquinoline group of alkaloids, has been synthesized by a route which can be adapted to provide asymmetric syntheses of thes alkaloids.
