123796-95-2Relevant academic research and scientific papers
Silver-Mediated Direct C-H Cyanation of Terminal Alkynes with N-Isocyanoiminotriphenylphosphorane
Wang, Hannan,Mi, Pengbing,Zhao, Wanjun,Kumar, Ravi,Bi, Xihe
, p. 5613 - 5616 (2017)
A direct cyanation of terminal alkynes for the synthesis of propionitrile derivatives, with the aid of silver salt using water additive, has been achieved. The cyano source used is N-isocyanoiminotriphenylphosphorane, which is nontoxic, safe, and easy to handle. This protocol is characterized by its operational simplicity, high efficiency with excellent yields, broad substrate scope, and greater functional group tolerance.
Synthesis of Conjugated Acetylenic Nitriles via Intramolecular Wittig reaction of Some Oxoylids
Yadla, R.,Rao, Jampani Madhusudana
, p. 1125 - 1127 (2007/10/02)
The preparation of 3-(adamantan-1-yl)-; 3-(2-ethoxyphenyl)-; 3-(3,4-methylenedioxyphenyl)-; 3-(thien-2-yl)- and (E)5-phenyl-pent-4-en-2-yne nitriles via in vacuo thermal decomposition of adamantan-1-carbonyl-; 2-ethoxybenzoyl-; 3,4-methylenedioxy-benzoyl-; thien-2-oyl- and (E)3-phenyl-prop-2-enoyl-cyano-methylenetriphenylphosphoranes respectively is reported
