1238056-79-5

Basic information

• Product Name: pentafluorophenyl isatin-5-carboxylate
• Synonyms: pentafluorophenyl isatin-5-carboxylate
• CAS NO: 1238056-79-5
• Molecular Weight: 357.193
• Mol File: 1238056-79-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: pentafluorophenyl isatin-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: pentafluorophenyl isatin-5-carboxylate(1238056-79-5)
• EPA Substance Registry System: pentafluorophenyl isatin-5-carboxylate(1238056-79-5)

Safety Data

• Hazardous Substances Data: 1238056-79-5(Hazardous Substances Data)

Upstream product

• 25128-32-9 1H-indole-2,3-dione-5-carboxylic acid 
• 14533-84-7 pentafluorophenyl trifloroacetate 

Relevant articles and documents

Synthesis and cytotoxicity of novel indirubin-5-carboxamides

Indirubins have been reported to act as potent inhibitors of protein kinases relevant to tumorigenesis and of tumor cell growth, but their development to antitumor drugs suffer from their poor water solubility. We synthesized a novel class of indirubin derivatives, indirubin-5-carboxamides, carrying amide substituents with basic centers. Quaternization or protonation of these alkylamino substituents provided indirubins with significantly improved solubility without loss of bioactivity.