123806-65-5

Basic information

• Product Name: Cyclopropanecarboxylic acid, 1-amino-2-phenyl-, methyl ester, (1S-trans)-
• Synonyms: Cyclopropanecarboxylic acid, 1-amino-2-phenyl-, methyl ester, (1S-trans)-
• CAS NO: 123806-65-5
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.22642
• Product Categories: AMINOACID
• Mol File: 123806-65-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopropanecarboxylic acid, 1-amino-2-phenyl-, methyl ester, (1S-trans)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid, 1-amino-2-phenyl-, methyl ester, (1S-trans)-(123806-65-5)
• EPA Substance Registry System: Cyclopropanecarboxylic acid, 1-amino-2-phenyl-, methyl ester, (1S-trans)-(123806-65-5)

Safety Data

• Hazardous Substances Data: 123806-65-5(Hazardous Substances Data)

Upstream product

• 123806-62-2 C₁₉H₁₉NO₄ 
• 86087-19-6 (1S,2R)-1-Benzyloxycarbonylamino-2-phenyl-cyclopropanecarboxylic acid 
• 86014-29-1 N-(benzyloxycarbonyl)-(2RS)-cyclopropyl-E-phenylalanine 
• 100-42-5 styrene 
• 1036637-32-7 methyl (1S,2R)-1-nitro-2-phenylcyclopropanecarboxylate 
• 150351-77-2 (Z,S)-1-Acetyl-3-benzylidene-6-(1-methylethyl)piperazine-2,5-dione 
• 72397-56-9 (2R)-dimethyl 2-phenylcyclopropane-1,1-dicarboxylate 
• 180322-84-3 monomethyl (1S,2R)-2-phenylcyclopropane-1,1-dicarboxylate 
• 180322-87-6 1-(methoxycarbonyl)-2-phenylcyclopropanecarboxylic acid 

Downstream Products

• 143796-77-4 C₂₂H₃₂N₂O₅ 
• 143796-76-3 C₂₃H₃₃N₃O₅S 
• 151910-11-1 (1S,2R)-1--2-phenylcyclopropane-1-carboxylic acid 
• 86087-21-0 (1S,2R)-(E)-(+)-1-amino-2-phenyl-1-cyclopropane-1-carboxylic acid hydrochloride 
• 151910-10-0 (1S,2R)-(E)-methyl 1-carbonyl>amino>-2-phenylcyclopropane-1-carboxylate 
• 150408-99-4 (1S,2R)-1-[(R)-2-(Adamantan-2-yloxycarbonylamino)-3-(1H-indol-3-yl)-2-methyl-propionylamino]-2-phenyl-cyclopropanecarboxylic acid methyl ester 

Relevant articles and documents

A formyl peptide substituted with a conformationally constrained phenylalanine residue evokes a selective immune response in human neutrophils

Formyl-Met-Leu-Phe-OH (fMLP) binds to formyl peptide receptors, FPR1 and FPR2, and evokes migration and superoxide anion production in human neutrophils. To obtain a more effective and selective ligand, fMLP analogs in which the Phe residue was substitute

Preparation of dipeptoid mimetics for the tetrapeptide cholecystokinin, CCK(30-33)

The diastereoselective synthesis of 2,3-methanophenylalanine methyl esters (5) has been achieved in 58% yield. The preparation of the dehydropeptides (1, R = Me; 2, R = H) and the cyclopropylpeptides (3, R = Me; 4, R = H) possessing good binding affinities for the CCK-A and CCK-B receptors is described. Conformational studies of the dipeptide esters 1 and 3 indicated the presence of a β-turn within the peptide backbone, although there was no preference in type. The Phe and Trp moieties, however, did prefer to be situated on the same side of the peptide turn which is favourable for receptor binding.