1238073-93-2Relevant academic research and scientific papers
First synthesis and antiprotozoal activities of divinyl sulfone-modified carbohydrates
Pal, Tarun Kumar,Dey, Tuli,Chakrabarty, Arindam,Dey, Debanjana,Ghosh, Sudip K.,Pathak, Tanmaya
supporting information; experimental part, p. 3777 - 3780 (2010/08/20)
Divinyl sulfone-modified carbohydrates have been synthesized for the first time by reacting easily available carbohydrate epoxides with thioethanol in a regiospecific fashion. One of the modified divinyl sulfones initiated significant cell death in Entamoeba species and the influence of the anomeric configurations on the biological activities of these sugar-derived divinyl sulfones has been highlighted. The most active compound in this series was found to be devoid of any toxicity.
