123809-99-4

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 7585-39-9 β‐cyclodextrin 
• 95509-72-1 6^A,6^C-ditosyl-β-CD 
• 95475-65-3 6^A,6^D-ditosyl-β-CD 

Relevant academic research and scientific papers

Specific Preparation and Structure Determination of 3A,3C,3E-Tri-O-sulfonyl-β-cyclodextrin

A reaction of β-cyclodextrin with β-naphthylsulfonyl chloride in alkaline aqueous acetonitrile gave only one isomer (3A,3C,3E-trisulfonate, 17.8percent) of five 3,3,3-tri-O-sulfonyl-β-cyclodextrins.The isomer was converted to 3A,6A:3C,6C:3E,6E-trianhydro-β-cyclodextrin, the structure of which was assigned by comparing its spectral and HPLC data of the trianhydro-β-cyclodextrin with those of all authentic 3,6:3,6:3,6-trianhydro-β-cyclodextrins prepared by the reactions of known 6-tri-O-sulfonylated β-cyclodextrins with aqueous alkali.

Regioisomeric 6A,6X,6Y-Tri-O-sulfonylated β-Cyclodextrin

All of five regioisomeric 6A,6X,6Y-tri-O-(p-toluenesulfonyl)-β-cyclodextrins were prepared, isolated, and their structures were determined through a combination of the extended Koerner method, 3,6-anhydration, and the Taka amylase A-catalyzed hydrolysis.