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123811-83-6

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123811-83-6 Usage

General Description

(+/-)-TRANS-N-BOC-4-METHYL-PIPECOLINIC ACID is a chemical compound with a molecular formula C14H25NO4. It is an organic acid derivative that is commonly used in the synthesis of pharmaceuticals and other biologically active compounds. (+/-)-TRANS-N-BOC-4-METHYL-PIPECOLINIC ACID is also known as 4-Methyl trans-4-[(tert-butoxycarbonyl)amino]piperidine-2-carboxylic acid. It is a crystalline solid with a white to off-white color, and it is sparingly soluble in water but more soluble in organic solvents. (+/-)-TRANS-N-BOC-4-METHYL-PIPECOLINIC ACID has potential applications in the pharmaceutical industry as a building block for the synthesis of various drugs and biologically active molecules.

Check Digit Verification of cas no

The CAS Registry Mumber 123811-83-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,8,1 and 1 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 123811-83:
(8*1)+(7*2)+(6*3)+(5*8)+(4*1)+(3*1)+(2*8)+(1*3)=106
106 % 10 = 6
So 123811-83-6 is a valid CAS Registry Number.

123811-83-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (+/-)-TRANS-N-BOC-4-METHYL-PIPECOLINIC ACID

1.2 Other means of identification

Product number -
Other names (+/-)-CIS-N-BOC-4-METHYL-PIPECOLINIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:123811-83-6 SDS

123811-83-6Relevant articles and documents

HEMIASTERLIN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF CANCER

-

Paragraph 0133; 0134, (2016/08/17)

The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R 1 -R 7 , X 1 , X 2 , R, Q, and n are as defined herein.

An Improved Synthesis of Homoproline and Derivatives

Shuman, Robert T.,Ornstein, Paul L.,Paschal, Jonathan W.,Gesellchen, Paul D.

, p. 738 - 741 (2007/10/02)

An improved, general synthesis of substituted homoprolines has been developed by using readily available substituted pyridines (1).A key step in this synthetic procedure involves the known conversion of pyridine-N-oxides to 2-cyanopyridines (3) in nearly quantitative yields.The resulting nitriles are hydrolyzed to the corresponding pyridine-2-carboxylic acids (4).Subsequent reduction of the aromatic ring with PtO2/H2 gives the homoprolines (5) in good yields as racemic cis isomers.This procedure also can be utilized for the preparation of 5,6-benzohomoprolines fromthe appropriate quinoline precursors.The N-tert-butyloxycarbonyl (Boc) derivatives of these amino acids (useful intermediates for peptide synthesis) were also prepared in good yields.

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