123821-09-0

Basic information

• Product Name: (1S,2R,6S,7R)-7,10,10-Trimethyl-4-((1S,6S)-3,4,6-trimethyl-cyclohex-3-enyl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]dec-4-ene
• Synonyms: (1S,2R,6S,7R)-7,10,10-Trimethyl-4-((1S,6S)-3,4,6-trimethyl-cyclohex-3-enyl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]dec-4-ene
• CAS NO: 123821-09-0
• Molecular Weight: 301.472
• Mol File: 123821-09-0.mol

Chemical Properties

• CAS DataBase Reference: (1S,2R,6S,7R)-7,10,10-Trimethyl-4-((1S,6S)-3,4,6-trimethyl-cyclohex-3-enyl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]dec-4-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R,6S,7R)-7,10,10-Trimethyl-4-((1S,6S)-3,4,6-trimethyl-cyclohex-3-enyl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]dec-4-ene(123821-09-0)
• EPA Substance Registry System: (1S,2R,6S,7R)-7,10,10-Trimethyl-4-((1S,6S)-3,4,6-trimethyl-cyclohex-3-enyl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]dec-4-ene(123821-09-0)

Safety Data

• Hazardous Substances Data: 123821-09-0(Hazardous Substances Data)

Upstream product

• 129064-54-6 (1S,2R,6S,7R)-5-Benzyl-7,10,10-trimethyl-4-((1R,2R,3S,4S)-3-methyl-bicyclo[2.2.1]hept-5-en-2-yl)-3-oxa-5-azonia-tricyclo[5.2.1.0^2,6]dec-4-ene; bromide 
• 129064-56-8 (1R,2R,3S,4S)-3-Methyl-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,3S,4R)-3-benzyloxycarbonylamino-4,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 129064-57-9 (1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,3S,4R)-3-benzyloxycarbonylamino-4,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 129064-55-7 (1R,2R,3S,4S)-3-Methyl-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,3S,4R)-3-benzylamino-4,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 123820-99-5 (1R,3R,exo)-N-benzyl-2-imino-3-hydroxy-1,7,7-trimethylbicyclo<2.2.1>heptane 
• 123821-00-1 (1R,2S,3R,exo)-N-benzyl-2-amino-3-hydroxy-1,7,7-trimethylbicyclo<2.2.1>heptane 
• 123821-01-2 (E)-But-2-enoic acid ((1R,2S,3R,4S)-3-hydroxy-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-amide 
• 123879-93-6 exo,exo-2-amino-3-hydroxy-camphor 
• 28357-11-1 (+)-3R-exo-hydroxycamphor 
• 10334-26-6 (R)-camphorquinone 
• 464-49-3 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 
• 123821-03-4 (1S,2R,6S,7R)-7,10,10-Trimethyl-4-((E)-propenyl)-3-oxa-5-aza-tricyclo[5.2.1.0^2,6]dec-4-ene 
• 513-81-5 2,3-dimethyl-buta-1,3-diene 

Relevant articles and documents

α,β-unsaturated oxazolines, a powerful tool in asymmetric diels-alder cycloadditions

α,β-Unsaturated oxazolines 10, 12, and 16, activated with trifluoroacetic anhydride, proved to be very powerful dienophiles toward various dienes such as 17-23 including Danishefsky type diene. The reactions were performed generally between -100 and -20 °C and the diastereoselectivity is usually better than 90%.

CHIRAL α,β-UNSATURATED OXAZOLINES IN THE ASYMMETRIC DIELS-ALDER REACTION

α,β-Unsaturated oxazolines derived from (+)-camphor become powerful dienophiles in asymmetric Diels-Alder reaction after activation with trifluoroacetic anhydride.