1238331-74-2

Upstream product

• 1238331-97-9 3-(1-nitro-2-naphthylamino)benzonitrile 
• 6952-59-6 3-cyanobromobenzene 
• 606-57-5 1-nitro-2-naphthylamine 
• 1238331-98-0 3-(1-amino-2-naphthylamino)benzonitrile 
• 1663-67-8 malonoyl dichloride 

Downstream Products

• 1238331-78-6 5-(3-cyanophenyl)-1-methyl-1H-naphtho[1,2-b][1,4]diazepin-2,4(3H,5H)-dione 
• 1238331-79-7 5-(3-cyanophenyl)-1,3-dimethyl-1H-naphtho[1,2-b][1,4]diazepin-2,4(3H,5H)-dione 
• 1239578-65-4 5-[3-(1H-Tetrazol-5-yl)phenyl]-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione 
• 1239578-78-9 5-[3-(5-Oxo-4H-[1,2,4]oxadiazol-3-yl)phenyl]-1H-naphtho[1,2-b][1,4]diazepin-2,4(3H,5H)-dione 
• 1239578-87-0 5-[3-(N-hydroxyamidino)phenyl]-1H-naphtho[1,2-b][1,4]diazepin-2,4(3H,5H)-dione 
• 1239578-79-0 5-[3-(5-Thioxo-4H-[1,2,4]oxadiazol-3-yl)phenyl]-1H-naphtho[1,2-b][1,4]diazepin-2,(3H,5H)-dione 
• 1239578-76-7 5-[3-(2-Methyl-2H-tetrazol-5-yl)phenyl]-1H-naphtho[1,2-b][1,4]diazepin-2,4(3H,5H)-dione 
• 1239578-77-8 5-[3-(1-methyl-1H-tetrazol-5-yl)phenyl]-1H-naphtho[1,2-b][1,4]diazepin-2,4(3H,5H)-dione 

Relevant academic research and scientific papers

DIAZEPINEDIONE DERIVATIVE

A diazepinedione derivative represented by the formula (I) or a pharmacologically acceptable salt thereof is used as a P2X4 receptor antagonist: wherein R1 represents a hydrogen atom, an alkyl group having' 1 to 8 carbon atoms, or the like, R2 and R3 represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, a halogen atom, or the like, R4 and R5 represent a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, or the like, and W represents tetrazole or the like.