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123843-67-4

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123843-67-4 Usage

Chemical Properties

Off-white Cryst

Check Digit Verification of cas no

The CAS Registry Mumber 123843-67-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,8,4 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 123843-67:
(8*1)+(7*2)+(6*3)+(5*8)+(4*4)+(3*3)+(2*6)+(1*7)=124
124 % 10 = 4
So 123843-67-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H2BrF2N/c8-4-1-6(9)5(3-11)7(10)2-4/h1-2H

123843-67-4 Well-known Company Product Price

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  • Alfa Aesar

  • (H32795)  4-Bromo-2,6-difluorobenzonitrile, 95%   

  • 123843-67-4

  • 250mg

  • 318.0CNY

  • Detail
  • Alfa Aesar

  • (H32795)  4-Bromo-2,6-difluorobenzonitrile, 95%   

  • 123843-67-4

  • 1g

  • 882.0CNY

  • Detail

123843-67-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Bromo-2,6-difluorobenzonitrile

1.2 Other means of identification

Product number -
Other names 1-bromo-4-cyano-3,5-difluoro-benzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:123843-67-4 SDS

123843-67-4Relevant articles and documents

CHEMICAL COMPOUNDS

-

Page/Page column 204-205, (2010/07/10)

The invention is directed to 6-(4-pyι?midinyl)-1 H-indazole derivatives. Specifically, the invention is directed to compounds according to Formula (I) wherein R1 - R4 are defined herein. The compounds of the invention are inhibitors of PDK1 and can be useful in the treatment of immune and metabolic diseases and disorders characterized by constitutively activated ACG kinases such as cancer and more specifically cancers of the breast, colon, and lung. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting PDK1 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

The Synthesis and Transition Temperatures of Some Fluoro-Substituted 4-Cyanophenyl and 4-Cyanobiphenyl-4'-yl 4-Pentyl- and 4-Butoxy-Benzoates

Gray, G. W.,Hird, M.,Lacey, D.,Toyne, K. J.

, p. 165 - 190 (2007/10/02)

A series of 4-cyanophenyl 4-X-benzoates and a series of 4-cyanobiphenyl-4'-yl 4-X-benzoates (X= pentyl, butoxy) have been prepared without fluoro-substitution and with mono-fluoro to tetra-fluoro-substitution; all possible combinations of substitution patterns at the positions ortho- to the cyano group and ortho- to the carboxylate group have been obtained in an attempt to determine the structural features which are responsible for some members of these series showing very large positive values of dielectric anisotropy.The synthesis of novel precursors required for the preparation of these esters is described and the melting points and transition temperatures of the esters are discussed and an explanation is provided for the variation of Tn-1 values with position and extent of fluoro-substitution. - Keywords: Fluoro-substitution, phenyl and biphenyl benzoates, terminal cyano namatogens.

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