123852-10-8 Usage
Description
2,2-Dimethylbutanoic Acid [1S-[1a,3a,4,4aa,7,8(2S,4S)]]-4-Chloro-8-[2-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-dimethyl-1-naphthalenyl Ester is a complex organic compound with a unique molecular structure. It is characterized by its brown oil appearance and serves as an intermediate in the synthesis of pharmaceutical compounds.
Uses
Used in Pharmaceutical Industry:
2,2-Dimethylbutanoic Acid [1S-[1a,3a,4,4aa,7,8(2S,4S)]]-4-Chloro-8-[2-[4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]tetrahydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,4,4a,7,8,8a-octahydro-4a-hydroxy-3,7-dimethyl-1-naphthalenyl Ester is used as an intermediate for the preparation of Simvastatin analogs. These analogs act as HMG-CoA reductase inhibitors, playing a crucial role in the regulation of cholesterol biosynthesis in the liver. By inhibiting this enzyme, Simvastatin analogs help lower low-density lipoprotein (LDL) cholesterol levels, which is essential for the management and prevention of cardiovascular diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 123852-10-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,8,5 and 2 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 123852-10:
(8*1)+(7*2)+(6*3)+(5*8)+(4*5)+(3*2)+(2*1)+(1*0)=108
108 % 10 = 8
So 123852-10-8 is a valid CAS Registry Number.
InChI:InChI=1/C31H53ClO6Si/c1-11-30(7,8)28(34)37-24-16-20(3)27(32)31(35)15-14-19(2)23(26(24)31)13-12-21-17-22(18-25(33)36-21)38-39(9,10)29(4,5)6/h14-15,19-24,26-27,35H,11-13,16-18H2,1-10H3/t19-,20+,21+,22+,23-,24-,26-,27-,31-/m0/s1
