1238575-89-7Relevant academic research and scientific papers
Four-component catalyst-free reaction in water: Combinatorial library synthesis of novel 2-amino-4-(5-hydroxy-3-methyl-1H-pyrazol-4-yl)-4H-chromene-3- carbonitrile derivatives
Kumaravel, Kandhasamy,Vasuki, Gnanasambandam
, p. 1945 - 1947 (2009)
A catalyst-free combinatorial library of novel 2-amino-4-(5-hydroxy-3- methyl-1H-pyrazol-4-yl)-4H-chromene-3-carbonitrile derivatives has been developed by a four-component reaction between hydrazine hydrate (1), ethyl acetoacetate (2), 2-hydroxybenzaldeh
Synergetic effects of naturally sourced metal oxides in organic synthesis: a greener approach for the synthesis of pyrano[2,3-c]pyrazoles and pyrazolyl-4H-chromenes
Shinde, Sachin K.,Patil, Megha U.,Damate, Shashikant A.,Patil, Suresh S.
, p. 1775 - 1795 (2017/12/06)
Abstract: A clean and more economic protocol for the synthesis of pyrano[2,3-c]pyrazoles and pyrazolyl-4H-chromenes has been carried out using bael fruit ash (BFA) as a non-conventional natural catalyst in aqueous condition at ambient temperature. The catalyst was obtained from renewable resources by simple thermal treatment to dry rind of Aegle marmelos (Bael) fruit and formation of its active phase was confirmed by AAS, DSC-TGA, XRD, FT-IR, and SEM techniques. The BFA catalyst was found to be a green, highly active, easily biodegradable, and recyclable without loss of activity after the fifth run. The methodology provides an alternative platform to the conventional catalyzed process. Graphical Abstract: [Figure not available: see fulltext.].
