1238587-83-1Relevant academic research and scientific papers
One-pot synthesis of aminoenone via direct reaction of the chloroalkyl enone with NaN3: Rapid access to polycyclic alkaloids
Zhao, Yu-Ming,Gu, Peiming,Tu, Yong-Qiang,Zhang, Hai-Jun,Zhang, Qing-Wei,Fan, Chun-An
supporting information; experimental part, p. 5289 - 5295 (2010/10/19)
(Figure presented) A new one-pot procedure for the preparation of aminoenone from chloroalkyl enone and sodium azide was demonstrated. The structure of the presumed triazoline intermediate in this process was confirmed by X-ray analysis for the first time. As the application of this methodology, the synthesis of polycyclic alkaloid hexahydroapoerysopine (1a) was achieved through an efficient synthetic route.
