123877-24-7Relevant articles and documents
Carbenoid pathways in copper-catalyzed intramolecular cyclopropanations of phenyliodonium ylides
Mueller, Paul,Bolea, Christelle
, p. 1093 - 1111 (2001)
The enantioselectivity of the copper-catalyzed intramolecular cyclopropanation of allyl diazomalonates and the corresponding phenyliodonium ylides was investigated with a series of chiral, non-racemic ligands. The reaction of 6b in the presence of the bis[dihydrooxazole] ligand Xa in refluxing 1,2-dichloroethane proceeded to 8b with an enantiomer excess (ee) of up to 72% under optimized conditions. In contrast, 8b resulting from reaction of ylide 7b with the same ligand, but in CH2Cl2 at 0°, had an ee of only 30%. With other ligands, diazomalonate 6b reacted with a lower enantioselectivity than ylide 7b, however. The intramolecular cyclopropanation of the acetoacetate-derived phenyliodonium ylide 15b afforded 16b with 68% ee with ligand Xa, but the corresponding diazo compound was unreactive when exposed to chiral copper catalysts. The observation of asymmetric induction in the Cu-catalyzed reactions of the ylides 7 and 15 is consistent with a carbenoid mechanism however, the discrepancy of the enantioselectivities observed between diazomalonate 6b and ylide 7b suggests a competing unselective pathway for cyclopropanation outside of the coordination sphere of copper.
A robust microporous metal-organic framework constructed from a flexible organic linker for highly selective sorption of methanol over ethanol and water
Huang, Qian,Cai, Jianfeng,Wu, Hui,He, Yabing,Chen, Banglin,Qian, Guodong
, p. 10352 - 10355 (2012)
A microporous metal-organic framework MOF 1 [Zn(L)2(methanol) 2] (H2L = (1R,3S)-1,2,2-trimethyl-3-(pyridin-4- ylcarbamoyl)cyclopentanecarboxylic acid) constructed from a flexible Zn 2+ node and a flexible organic linker L was obtained by solvothermal reaction of diamond topology, and exhibits highly selective sorption of methanol over ethanol and water.
NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
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Page/Page column 145-146; 147-148, (2010/06/11)
The present application relates to isothiazolylidene containing compounds of Formula (I) wherein R1, R2, R3, R4, and L are as defined in the specification, compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions.
Two chiral nonlinear optical coordination networks based on interwoven two-dimensional square grids of double helices
Huang, Qian,Yu, Jiancan,Gao, Junkuo,Rao, Xingtang,Yang, Xiuli,Cui, Yuanjing,Wu, Chuande,Zhang, Zhangjing,Xiang, Shengchang,Chen, Banglin,Qian, Guodong
scheme or table, p. 5291 - 5296 (2011/10/12)
Two new chiral two-dimensional coordination networks, ZnL 2(H2O)2 (1) and CdL2(H 2O)2 (2) [L = 1,2,2-trimethyl-3-(pyridin-4-ylcarbamoyl) cyclopentanecarboxylic acid], have been synthesized and structurally characterized by single X-ray structure analysis, featuring very unusual interwoven (4,4) square grids of double helices. The frameworks exhibit high thermal stability as confirmed by thermogravimetric analysis and powder X-ray diffraction studies. The unique chiral networks attributed to the chiral organic linker have led to their nonlinear optical properties.
Chiral carboxylic acid ligands derived from camphoric acid
Moloney, Mark G.,Paul, Diana R.,Thompson, Russell M.,Wright, Emma
, p. 2551 - 2562 (2007/10/03)
Versatile and convenient preparations of chiral carboxylic acid ligands, derived from camphoric acid, are described, either by esterification of camphoric dichloride or by a regioselective opening of the corresponding anhydride by a variety of alcohols or diols.
