123878-19-3 Usage
Description
(-)-Canadalisol is a synthetic analogue of S-(-)-Canadine, a protoberberine alkaloid that has the ability to potently block functional KATP channels natively expressed on midbrain dopamine neurons.
Uses
Used in Pharmaceutical Industry:
(-)-Canadalisol is used as a pharmaceutical agent for its ability to block functional KATP channels on midbrain dopamine neurons. This property makes it a potential candidate for the development of treatments targeting neurological disorders and conditions related to dopamine regulation.
Check Digit Verification of cas no
The CAS Registry Mumber 123878-19-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,8,7 and 8 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 123878-19:
(8*1)+(7*2)+(6*3)+(5*8)+(4*7)+(3*8)+(2*1)+(1*9)=143
143 % 10 = 3
So 123878-19-3 is a valid CAS Registry Number.
123878-19-3Relevant articles and documents
THE PYROLYSIS AND PHOTOLYSIS OF THE PROTOPINE TYPE ALKALOID N-OXIDES. THE SYNTHESIS OF THE SECOBERBINES AND BENZOPHENANTHRIDINES
Iwasa, Kinuko,Takao, Narao
, p. 1535 - 1539 (2007/10/02)
The pyrolysis of the N-oxides of the protopine-type alkaloids afforded three products, one of which was converted to the naturally occurring secoberbines.The photolysis of the N-oxides of the protopines supplied the benzophenanthridines as well as the one of the pyrolysis products.
