123895-42-1 Usage
General Description
2-(bromomethyl)-5-(trifluoromethyl) benzothiazole is a chemical compound with the molecular formula C9H5BrF3NS. It is a benzothiazole derivative with a bromine atom and a trifluoromethyl group attached to the benzene ring. 2-(BROMOMETHYL)-5-(TRIFLUOROMETHYL) BENZOTHIAZOLE is used in the synthesis of various pharmaceuticals and agrochemicals. It has also been studied for its potential applications in the development of organic light-emitting diodes (OLEDs) and as a fluorescent probe for the detection of metal ions in biological systems. Additionally, it has been investigated for its antimicrobial and anti-cancer properties. The compound's unique structure and properties make it a versatile building block in organic synthesis and a target for further research in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 123895-42-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,8,9 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 123895-42:
(8*1)+(7*2)+(6*3)+(5*8)+(4*9)+(3*5)+(2*4)+(1*2)=141
141 % 10 = 1
So 123895-42-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H5BrF3NS/c10-4-8-14-6-3-5(9(11,12)13)1-2-7(6)15-8/h1-3H,4H2
123895-42-1Relevant articles and documents
Highly selective aldose reductase inhibitors. II. Optimization of the aryl part of 3-(arylmethyl)-2,4,5-trioxoimidazolidine-1-acetic acids
Kotani, Takayuki,Ishii, Akira,Nagaki, Yasuhiro,Toyomaki, Yoshio,Yago, Hisashi,Suehiro, Seishi,Okukado, Nobuhisa,Okamoto, Kaoru
, p. 297 - 304 (2007/10/03)
Accumulation of intracellular sorbitol, the product of glucose reduction catalyzed by aldose reductase (AR) [EC 1.1.1.21], is thought to be the main culprit in the development of diabetic complications. A series of 3- arylalkyl-2,4,5-trioxoimidazolidine-1-acetic acids was prepared and tested for inhibitory activities towards AR and aldehyde reductase (ALR) [EC 1.1.1.2]. These derivatives showed strong inhibitory activity against AR without markedly inhibiting ALR. In particular, the compounds with 3- nitrophenyl, 4-chloro-3-nitrophenyl, and chloro-substituted benzothiazolyl groups as the aryl part showed powerful AR-inhibitory activity. The chloro- substituted benzothiazolyl compound showed an AR selectivity of more than 5000 fold.