1239116-72-3Relevant academic research and scientific papers
Pd-catalyzed one-pot chemoselective hydrogenation protocol for the preparation of carboxamides directly from azides
Bavikar, Sudhir N.,Salunke, Deepak B.,Hazra, Braja G.,Pore, Vandana S.,Thierry, Josiane,Dodd, Robert H.
, p. 3815 - 3819 (2010)
Carboxamides were obtained efficiently in high yields from azides on reaction with the corresponding pre-formed activated carboxylic acids in a single-step reductive transformation using hydrogen atmosphere (balloon) under Pd/BaSO4 or Pd/CaCO3 catalysis. The method is highly chemoselective and compatible with extremely labile functional groups such as benzyl carbamates, benzyl ethers, benzyl esters, and olefins.
