1239356-17-2Relevant academic research and scientific papers
An efficient method to construct 2-vinylidenyl cyclobutanone derivatives and its structural determination
Zhang, Yu-Xin,Guo, Lin,Wang, Ya-Hui,Zhu, Li-Li,Chen, Zi-Li
, p. 241 - 245 (2010)
2-Vinylidenyl cyclobutanone derivatives 5 can be readily synthesized from the dialkynyl cyclopropanols 4 through a consecutive process of 1,6-diynes carbocyclization and ring enlargement of cyclopropnaol unit by using AuCl(PPh3)/AgPF6 as catalyst in DCE a
Gold-catalyzed cycloisomerization of yne-vinylidenecyclopropanes: A three-carbon synthon for [3+2] cycloadditions
Yuan, Wei,Tang, Xiangying,Wei, Yin,Shi, Min
supporting information, p. 3198 - 3204 (2014/03/21)
A novel type of yne-vinylidenecyclopropanes (VDCPs) has been synthesized and applied in gold-catalyzed cycloisomerization reactions. It was found that these compounds can undergo an intramolecular cycloisomerization and perform as a three-carbon synthon for [3+2] cycloaddition under gold catalysis to give fused [4.3.0] and [5.3.0] bicyclic derivatives and VDCP rearranged products in moderated to good yields under mild conditions. The substrate scope of these novel transformations has been explored and plausible reaction mechanisms have been presented on the basis of deuterium labeling experiments and DFT calculations. Gold cats: A novel type of yne-vinylidenecyclopropanes (VDCPs) has been synthesized. These compounds can undergo an intramolecular cycloisomerization and perform as a three-carbon synthon for [3+2] cycloadditions under gold catalysis to give fused [4.3.0] and [5.3.0] bicyclic derivatives and VDCP-rearranged products in moderated to good yields under mild conditions (see scheme).
