1239374-08-3Relevant academic research and scientific papers
Amination of aryl iodides using a fluorous-tagged ammonia equivalent
Nielsen, Simon Dalsgaard,Smith, Garrick,Begtrup, Mikael,Kristensen, Jesper L.
experimental part, p. 3704 - 3710 (2010/09/05)
A fluorous-tagged ammonia equivalent for the Cu-catalyzed amination of aryl iodides is described in which N-Boc-protected anilines are produced in high overall yield and purity. All purification steps are performed using Fluorous SolidPhase Extraction (F-SPE) greatly simplifying and speeding up the isolation of the desired products.
