1239442-07-9Relevant academic research and scientific papers
Highly recyclable chemo/biocatalyzed cascade reactions with ionic liquids: One-pot synthesis of chiral biaryl alcohols
Gauchot, Vincent,Kroutil, Wolfgang,Schmitzer, Andreea R.
, p. 6748 - 6751 (2010)
(Figure Presented) Mix and match : We report a cascade reaction sequence for the highly enantio- and diastereoselective synthesis of biaryl alcohols, employing a Suzuki coupling followed by a biocatalytic reduction in a biphasic system containing ionic liquids (ILs; see figure). We demonstrate the recyclability of the IL phase as well as the aqueous phase up to four cycles with only a negligible deactivation of reactivity and selectivity.
