1239447-39-2Relevant articles and documents
Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway
Mahindroo, Neeraj,Connelly, Michele C.,Punchihewa, Chandanamali,Yang, Lei,Yan, Bing,Fujii, Naoaki
experimental part, p. 4801 - 4811 (2010/08/06)
We have previously reported small-molecule inhibitors of Gli1-mediated transcription, an essential down-stream element of the Hh pathway. We created new derivatives of the previous compounds aiming to improve the druggable properties. The new compounds, a