1239461-89-2Relevant academic research and scientific papers
The design and synthesis of a novel organophosphorus compound containing the structure of both β-amino acid and β-aminophosphonate
Teng, Han Bing
scheme or table, p. 810 - 812 (2011/11/13)
A novel organophosphorus compound containing the structure of both b-amino acid and b-aminophosphonate is designed and synthesized. Arbuzov reaction with P(OEt)3, the N-Boc protected iodide 3 cannot provide the desired product but 2-oxazolidinone 4 because of the neighboring-group participation of the Boc moiety. To avoid the intramolecular participation of the carbamates, the Ts protecting group is employed and the Ts-protected iodide 5 affords the target product successfully.
