123956-65-0 Usage
Uses
Used in Organic Synthesis:
3'-O-t-ButyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-N4-acetyl cytidine is used as a protective agent for hydroxyl groups in organic synthesis. Its silyl ether structure allows for the protection of sensitive functional groups during chemical reactions, preventing unwanted side reactions and facilitating the synthesis of complex molecules.
Used in DNA Synthesis:
In the field of DNA synthesis, 3'-O-t-ButyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-N4-acetyl cytidine is used as a protective agent for hydroxyl groups. The 4,4'-dimethoxytrityl group provides protection during the synthesis process, ensuring the accurate incorporation of cytidine derivatives into DNA sequences. This protection is crucial for maintaining the integrity and stability of the synthesized DNA molecules.
Used in Genetic Research:
3'-O-t-ButyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-N4-acetyl cytidine is used as a key compound in the study of genetics and biochemistry. Its unique structure and protective properties make it an essential tool for researchers working on the synthesis, modification, and analysis of nucleic acids. 3'-O-t-ButyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-N4-acetyl cytidine contributes to the development of new genetic therapies, diagnostic tools, and understanding the molecular basis of genetic diseases.
Used in Biochemical Studies:
In biochemical research, 3'-O-t-ButyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-N4-acetyl cytidine is employed as a protective agent and a building block for the synthesis of various nucleosides. Its presence in biochemical studies aids in the investigation of nucleic acid interactions, enzyme mechanisms, and the development of new biocatalysts and biosensors. 3'-O-t-ButyldiMethylsilyl-5'-O-(4,4'-diMethoxytrityl)-N4-acetyl cytidine plays a vital role in advancing our understanding of biological processes at the molecular level.
Check Digit Verification of cas no
The CAS Registry Mumber 123956-65-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,9,5 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 123956-65:
(8*1)+(7*2)+(6*3)+(5*9)+(4*5)+(3*6)+(2*6)+(1*5)=140
140 % 10 = 0
So 123956-65-0 is a valid CAS Registry Number.
123956-65-0Relevant academic research and scientific papers
The synthesis of allyl- and allyloxycarbonyl-protected RNA phosphoramidites. Useful reagents for solid-phase synthesis of RNAs with base-labile modifications
Bogdan, Felicia M.,Chow, Christine S.
, p. 1897 - 1900 (2007/10/03)
The synthesis of allyl- and allyloxycarbonyl (AOC)-protected RNA phosphoramidites is reported. The use of allyl and AOC groups allows the chemistry of solid-phase RNA synthesis to be expanded to include base-labile modified nucleosides, such as acetylcytidine. The allyl- and AOC-protective chemistry can be further expanded for the construction of RNAs on solid supports and affinity columns.
