1239573-86-4Relevant academic research and scientific papers
Copper-catalyzed cascade syntheses of 2 H -benzo[ b ][1,4]thiazin-3(4 H)-ones and quinoxalin-2(1 H)-ones through capturing S and N atom respectively from AcSH and TsNH2
Chen, Dingben,Wang, Zhi-Jing,Bao, Weiliang
, p. 5768 - 5771 (2010)
A copper-catalyzed cascade method has been developed to synthesize the 2H-benzo[b][1,4]thiazin-3(4H)-ones from 2-halo-N-(2-halophenyl)-acetamides 1 and AcSH via the SN2/deacetylation/coupling process, and to synthesize the quinoxalin-2(1H)-ones from 1 and TsNH2 via the S N2/coupling/desulfonation process. The target products were obtained with diversity at three positions on their scaffolds.
