1239605-45-8

Basic information

• Product Name: trimethyl(6-phenylnaphthalen-2-yl)silane
• Synonyms: trimethyl(6-phenylnaphthalen-2-yl)silane
• CAS NO: 1239605-45-8
• Molecular Weight: 276.453
• Mol File: 1239605-45-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: trimethyl(6-phenylnaphthalen-2-yl)silane(CAS DataBase Reference)
• NIST Chemistry Reference: trimethyl(6-phenylnaphthalen-2-yl)silane(1239605-45-8)
• EPA Substance Registry System: trimethyl(6-phenylnaphthalen-2-yl)silane(1239605-45-8)

Safety Data

• Hazardous Substances Data: 1239605-45-8(Hazardous Substances Data)

Upstream product

• 100-58-3 phenylmagnesium bromide 
• 202831-66-1 6-bromo-N-phenylnaphthalene-2-amine 
• 18410-39-4 (6-methoxynaphthalen-2-yl)trimethylsilane 
• 591-51-5 phenyllithium 
• 591-50-4 iodobenzene 
• 18081-06-6 6-(trimethylsilyl)naphthalen-2-ol 

Relevant articles and documents

Nickel-Catalyzed Kumada Coupling of Boc-Activated Aromatic Amines via Nondirected Selective Aryl C-N Bond Cleavage

A nickel-catalyzed Kumada coupling of aniline derivatives was developed by selective cleavage of aryl C-N bonds under mild reaction conditions. Without preinstallation of an ortho directing group on anilines, the cross-coupling reactions of Boc-protected aromatic amines with aryl Grignard reagents afforded unsymmetric biaryls. Mechanistic studies by DFT calculations revealed that the nickel-mediated C-N bond cleavage is the rate-limiting step.

Aryl ether as a Negishi coupling partner: An approach for constructing C-C bonds under mild conditions

An etheric Negishi coupling: The first cross-coupling reaction between aryl alkyl ethers and dianion-type zincate reagents to afford biaryl compounds through selective cleavage of the etheric C(sp2)-O bond was developed. Dianion-type zincates showed excellent reactivity toward the aromatic ethers under mild conditions, with good functional group compatibility (see scheme). Copyright