1239669-41-0Relevant academic research and scientific papers
ortho-Substituted C-aryl glucosides as highly potent and selective renal sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors
Xu, Baihua,Feng, Yan,Lv, Binhua,Xu, Ge,Zhang, Lili,Du, Jiyan,Peng, Kun,Xu, Min,Dong, Jiajia,Zhang, Wenbin,Zhang, Ting,Zhu, Liangcheng,Ding, Haifeng,Sheng, Zelin,Welihinda, Ajith,Seed, Brian,Chen, Yuanwei
experimental part, p. 4422 - 4432 (2010/09/12)
A series of 2-substituted C-aryl glucosides have been synthesized and evaluated for inhibition of hSGLT1 and hSGLT2. Introduction of an appropriate ortho substituent at the proximal phenyl ring adjacent to the glycosidic bond was found to improve SGLT2 in
