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4-bromo-N-(2-(1H-imidazol-1-yl)-2-phenylethyl)benzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1239713-01-9

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1239713-01-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1239713-01-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,3,9,7,1 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1239713-01:
(9*1)+(8*2)+(7*3)+(6*9)+(5*7)+(4*1)+(3*3)+(2*0)+(1*1)=149
149 % 10 = 9
So 1239713-01-9 is a valid CAS Registry Number.

1239713-01-9Downstream Products

1239713-01-9Relevant academic research and scientific papers

Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2- phenylethyl)arylamides

Aboraia, Ahmed S.,Yee, Sook Wah,Gomaa, Mohamed Sayed,Shah, Nikhil,Robotham, Anna C.,Makowski, Bart,Prosser, David,Brancale, Andrea,Jones, Glenville,Simons, Claire

experimental part, p. 4939 - 4946 (2010/09/10)

A series of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides were prepared, using an efficient three- to five-step synthesis, and evaluated for their inhibitory activity against human cytochrome P450C24A1 (CYP24A1) hydroxylase. Inhibition ranged from IC50 0.3-72 μM compared with the standard ketoconazole IC50 0.52 μM, with the styryl derivative (11c) displaying enhanced activity (IC50 = 0.3 μM) compared with the standard, providing a useful preliminary lead for drug development.

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