1239727-90-2Relevant academic research and scientific papers
Metal-Free Synthesis of 2-Arylbenzothiazoles from Aldehydes, Amines, and Thiocyanate
Dey, Amrita,Hajra, Alakananda
supporting information, p. 1686 - 1689 (2019/03/11)
A highly efficient method for the synthesis of 2-arylbenzothiazoles has been developed using readily available aromatic amines, benzaldehydes, and NH4SCN as a sulfur source. A library of 2-arylbenzothiazoles with wide functional group compatibility has been synthesized in good yields through iodine-mediated oxidative annulation.
Pd(PPh3)4-catalyzed direct ortho-fluorination of 2-arylbenzothiazoles with an electrophilic fluoride N-fluorobenzenesulfonimide (NFSI)
Ding, Qiuping,Ye, Changqing,Pu, Shouzhi,Cao, Banpeng
, p. 409 - 416 (2014/01/06)
An efficient protocol was developed for regio-selective Pd-catalyzed direct ortho-fluorination of 2-arylbenzo[d]thiazoles using N-fluorobenzenesulfonimide (NFSI) as the F+ source, and l-proline as the crucial promoter. The present method offered a practical route to synthesize valuable fluorinated products, which are of potential importance in the pharmaceutical and agrochemical industries.
