1239766-87-0Relevant academic research and scientific papers
Concurrent Formation of N-H Imines and Carbonyl Compounds by Ruthenium-Catalyzed C-C Bond Cleavage of β-Hydroxy Azides
Lee, Jeong Min,Bae, Dae Young,Park, Jin Yong,Jo, Hwi Yul,Lee, Eunsung,Rhee, Young Ho,Park, Jaiwook
supporting information, p. 4608 - 4613 (2020/06/05)
A commercial cyclopentadienylrutenium dicarbonyl dimer ([CpRu(CO)2]2) efficiently catalyzes the formation of N-H imines and carbonyl compounds simultaneously from β-hydroxy azides via C-C bond cleavage under visible light. Density functional theory calculations for the cleavage reaction support the mechanism involving chelation of alkoxy azide species and liberation of nitrogen as the driving force. The synthetic utility of the reaction was demonstrated by a new amine synthesis promoted by chemoselective allylation of imine and synthesis of isoquinoline.
BiI3 mediated difunctionalization of α-methylstyrenes, including azidohydroxylation and azidoiodination
Hsueh, Nai-Chen,Chan, Chieh-Kai,Chang, Meng-Yang
, p. 1002 - 1008 (2018/01/27)
BiI3 mediated vicinal azidohydroxylation of α-methylstyrenes 1 with NaN3 in wet DMF affords β-azidoalcohols 4 in good yields. In dry DMF, β-azidoiodides 6 are also obtained by BiI3 mediated vicinal azidoiodination of α-met
Visible-Light-Promoted Metal-Free Aerobic Hydroxyazidation of Alkenes
Yang, Bo,Lu, Zhan
, p. 8362 - 8365 (2017/12/08)
A highly efficient visible-light-promoted metal-free aerobic hydroxyazidation of alkenes has been developed. This protocol was operationally simple with broad substrate scope using relatively simple and readily available starting materials, such as alkene
Preparation method of beta-azide alcohol compound
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Paragraph 0048; 0049; 0050; 0051; 0052; 0053-0054; 0067-0069, (2017/09/01)
The invention discloses a preparation method of a beta-azide alcohol compound. According to the method, an olefin compound shown in a formula I, an azide source shown in a formula II and a photocatalyst are mixed in a non-nucleophilic organic solvent; and
Resolution of 2,2-disubstituted epoxides via biocatalytic azidolysis
Molinaro, Carmela,Guilbault, Audrey-Anne,Kosjek, Birgit
scheme or table, p. 3772 - 3775 (2010/11/16)
A practical procedure for the enzymatic resolution of 2-alkyl-2-aryl- disubstituted epoxides using the Codex HHDH P2E2 enzyme and sodium azide is reported. This method allowed the synthesis of novel regio-and enantioselective 1-azido-2-arylpropan-2-ols in
