1239892-00-2Relevant academic research and scientific papers
Artificial metalloenzymes through cysteine-selective conjugation of phosphines to photoactive yellow protein
Laan, Wouter,Munoz, Bianca K.,Den Heeten, Rene,Kamer, Paul C. J.
scheme or table, p. 1236-1239+1159 (2011/03/23)
(Chemical Equation Presented) Pinning phosphines on proteins: A method for the cysteine-selective bioconjugation of phosphines has been developed. The photoactive yellow protein has been site-selectively functionalized with phosphine ligands and phosphine transition metal complexes to afford artificial metalloenzymes that are active in palladium-catalysed allylic nucleophilic substitution reactions.
