1239892-91-1Relevant academic research and scientific papers
Co(iii)(salen)-catalyzed HKR of two stereocentered alkoxy- and azido epoxides: A concise enantioselective synthesis of (S,S)-reboxetine and (+)-epi-cytoxazone
Reddy, R. Santhosh,Chouthaiwale, Pandurang V.,Suryavanshi, Gurunath,Chavan, Vilas B.,Sudalai, Arumugam
, p. 5012 - 5014 (2010)
The HKR of racemic syn- or anti- alkoxy- and azido epoxides catalyzed by Co(salen) complex affords a practical access to a series of enantioenriched syn- or anti- alkoxy- and azido epoxides and the corresponding 1,2-diols. This strategy has been successfully employed in the concise, enantioselective synthesis of bioactive molecules such as (S,S)-reboxetine and (+)-epi-cytoxazone.
